兔抗phf21a多ke隆抗体

backgr

ound:

zinc-finger proteins contain dna-binding domains&have a wide variety of functions, most of which encompass some form of tranional activation/repression. phf21a (phd finger protein 21a), also known as braf35-hdac complex protein bhc80, is a 680 amino acid nuclear protein that contains one phd-type zinc finger&one a.t hook dna-binding domain, suggesting involvement in tranional regulation events. phf21a is a component of the bhc complex, which is responsible for repressing tranion of neuron-specific genes in non-neuronal cells. the bhc complex acts as a chromatin modifier that deacetylates&demethylates specific sites on histones. phf21a may act as a scaffold within the bhc complex. predominantly expressed in brain, three isoforms of phf21a exist as a result of alternative splicing events.

applications:

elisa, ihc

name of antibody:

phf21a

immunogen:

fusion protein of human phf21a

full name:

phd finger protein 21a

synonyms:

bhc80; bm-006

swissprot:

q96bd5

elisa recomm

ended dilution:

5000-10000

ihc positive control:

human colorectal cancer&human ovarian cancer

ihc recommend dilution:

40-200